Definition

Titration

The gradual stepping up of a dose over weeks to limit side effects, set by a prescriber.

Titration is the process of starting a medication at a low dose and increasing it in stages, allowing the body to adjust and limiting side effects such as nausea. GLP-1 drugs are titrated over months from a small starting dose toward a maintenance dose. The same idea in reverse, tapering, is sometimes used when coming off. The schedule is always individualized by the prescriber based on response and tolerance.

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